STUDY OF FINGERPRINTS PATTERN IN BREAST CANCER PATIENTS INSHARKIA GOVERNORATE, A CASE –CONTROL RETROSPECTIVE CLINICAL STUDY.

Abstract

ABSTRACT
Background :Worldwide, breast cancer is the most frequently diagnosed life-threatening cancer in
women. In less-developed countries, it is the leading cause of cancer death in women; in developed
countries. Breast cancer is one of the most extensively studied cancers and its genetic basis is well
established.Dermatoglyphic traits are formed under genetic control early in development but may be
affected by environmental factors during first trimester of pregnancy. These patterns may represent the
genetic make up of an individual and therefore his/her predisposition to certain diseases. The finger and
palmar prints patterns have already beenstudied with respect to various genetic diseases such as the
Down's gsyndrome and Klinefeltersyndrome. The fingerprints can thus represent a simple, non
invasive anatomical marker of breast cancer risk.
Methods :This study was applied to fifty histopathologically-confirmed breast cancer patients and their
fingerprints patterns were assessed. At the same time , fifty age-matched controls were selected being
have no self or family history of breast cancer and the observations were recorded abd data were
collected.
Result :It was observed that whorl pattern is the most common fingerprints pattern to be identified in
breast cancer cases compared to controls. Also the quantitative difference in ridge count was
statistically important.
Conclusion : The pattern of fingerprints may be a useful tool in the future in identifying and also
screening of breast cancer.
Key Words : Breast cancer, Fingerprints, Genetics, Screening